[Clinical efficacy of ciprofloxacin 0.3%9 (Ciloxan) in the treatment of bacterial infections of the external eye segment].

Abstract

PURPOSE:

The main subject of the study was to evaluate efficacy of ciprofloxacin 0.3% ophthalmic solution (Ciloxan) in the treatment of bacterial conjunctivitis and surgical prophylaxis. Safety and comfort of topical ciprofloxacin treatment was also examined.

MATERIAL AND METHODS:

Two study arms: 99 patients with bacterial conjunctivitis (A group) and 48 patients awaiting cataract surgery (B group--total 147 subjects in both groups) received ciprofloxacin 0.3% ophthalmic solution (Ciloxan) 4 doses a day for seven days. Bacteriological evaluation was established before and after treatment for each eye.

RESULTS:

95 out of the 99 patients (96%) in the first arm were completely cured (all signs and symptoms of the bacterial conjunctivitis were eliminated). In the second arm complete eradication of bacterial flora was achieved in 46 out of 48 pretreated patients (96%).

CONCLUSIONS:

Topical ciprofloxacin 0.3% (iloxan) was found very effective and fast in reduction of typical signs and symptoms of bacterial conjunctivitis as well as in eradication of bacterial flora before surgery treatment.

• Authors: Andrzej Stankiewicz, Mariusz Kosatka, Arkadiusz Goś
• Journal: Klinika oczna (Klin Oczna) Vol. 105 Issue 6 Pg. 407-9 ( 2003) ISSN: 0023-2157 [Print] Poland
• Vernacular Title: Skuteczność kliniczna ciprofloksacyny 0,3% (Ciloxan) w leczeniu infekcji bakteryjnych aparatu ochronnego oka.
• PMID: 15049266 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Anti-Infective Agents
• Ophthalmic Solutions
• Ciprofloxacin

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Anti-Infective Agents (administration & dosage, therapeutic use)
• Antibiotic Prophylaxis
• Cataract Extraction
• Ciprofloxacin (administration & dosage, therapeutic use)
• Conjunctivitis, Bacterial (drug therapy)
• Eye Infections, Bacterial (drug therapy, microbiology)
• Female
• Humans
• Male
• Middle Aged
• Ophthalmic Solutions