[Efficacy of the Russian anthelmintic agent trichlorophen].

Abstract

Experiments have established the high efficacy of combinations of the micronized dosage form of trichlorophen, with albendazole or medamine in treating trichocephaliasis (its causative agent being Trichocephalus muris) in DBA/2st mice and that of trichlorophen in combination with azinox or fenasal in outbred albino mice with hymenolepiasis (its causative agent being Hymenolepis nana). These combinations are promising in treating patients with cestodosis and nemadosis, respectively.

• Authors: L V Fedianina, G A Gitsu, M N Lebedeva, B A Astaf'ev
• Journal: Meditsinskaia parazitologiia i parazitarnye bolezni (Med Parazitol (Mosk)) 2004 Jan-Mar Issue 1 Pg. 48-50 ISSN: 0025-8326 [Print] Russia (Federation)
• Vernacular Title: Potentsiruiushchie effecty otechestvennogo antigel'mintika trikhlofena.
• PMID: 15042750 (Publication Type: English Abstract, Journal Article)

Chemical References

• Anthelmintics
• Benzimidazoles
• Carbamates
• Chlorophenols
• azinox
• Praziquantel
• trichlorophene
• Niclosamide
• Albendazole
• carbendazim

Topics

• Administration, Oral
• Albendazole (therapeutic use)
• Animals
• Anthelmintics (administration & dosage, therapeutic use)
• Benzimidazoles (therapeutic use)
• Carbamates
• Chlorophenols (administration & dosage, therapeutic use)
• Drug Evaluation, Preclinical
• Drug Therapy, Combination
• Helminthiasis (drug therapy)
• Hymenolepiasis (drug therapy)
• Mice
• Mice, Inbred DBA
• Niclosamide (therapeutic use)
• Praziquantel (analogs & derivatives, therapeutic use)
• Trichuriasis (drug therapy)