Abstract | STUDY DESIGN: This is a case report with literature review. OBJECTIVE: SETTING: The department of Physical Medicine and Rehabilitation, University of North Carolina at Chapel Hill, USA. METHOD: A 24-year-old African-American male with long-standing incomplete paraplegia visited the wound clinic due to a pressure ulcer that had lasted for more than 1 year on the medial side of the right foot. Despite conservative management for almost 2 years after the initial visit, the ulcer is suspected to have undergone malignant transformation. Histological study led to the diagnosis of verrucous carcinoma that necessitated transtibial amputation on the right foot. RESULT: CONCLUSION: The possibility of malignant transformation should be kept in mind in cases of pressure ulcers that are unresponsive to treatment or that show morphological changes suspected to be cancerous. Furthermore, early detection and intervention increases the probability for successful outcome.
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Authors | M Y Lee, J C Shin, C I Park, D W Rha, T K Sastry |
Journal | Spinal cord
(Spinal Cord)
Vol. 42
Issue 7
Pg. 431-4
(Jul 2004)
ISSN: 1362-4393 [Print] England |
PMID | 15037863
(Publication Type: Case Reports, Journal Article)
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Topics |
- Adult
- Carcinoma, Verrucous
(etiology)
- Cell Transformation, Neoplastic
- Foot Ulcer
(complications)
- Humans
- Male
- Orthotic Devices
(adverse effects)
- Paraplegia
(complications)
- Pressure Ulcer
(complications)
- Skin Neoplasms
(etiology)
- Time Factors
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