Abstract |
To determine optimal indications for and clinical assessment of the significance of relaparotomy, the data of 304 women with malignant ovarian tumours (of epithelial origin, predominantly, 72%) who had undergone a 'second-look' operation were analysed. 'Second-look' relaparotomies were performed 10-22 months after the initial operation, on the following clinical indications: 1) clinical remission after initial combined treatment (surgery + chemotherapy) in cases where malignant cells are found at systematically performed cytological examinations of ??? or lavage from peritoneal surfaces of the Douglas cul-de-sac plus high levels of CA 125 in blood serum (8 patients with stages I and II, FIGO classification); 2) remission after adequate combined treatment and following 6-10 cycles of polychemotherapy, in order to decide whether to abandon or continue with treatment (13 patients with stages III and IV); 3) clinical remission following initial operation which was voluminously non-radical (117 patients); 4) suspicion of tumour recurrence after adequate combined treatment (114 patients); 5) no suspicion of cancer recurrence, though with ventral hernia or other pathology requiring relaparotomy (22 patients). Complications arising at the 'second-look' operation or during the postoperative period were observed in 29 of the 304 patients (9.5%), giving a postoperative mortality of 0.9%. According to experience, the positive significance of 'second-look' operations to optimize treatment of patients with malignant ovarian tumours is obvious.
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Authors | Bokhman YaV, V L Vinokurov, E I Gulo |
Journal | Acta obstetricia et gynecologica Scandinavica. Supplement
(Acta Obstet Gynecol Scand Suppl)
Vol. 155
Pg. 79-83
( 1992)
ISSN: 0300-8835 [Print] Denmark |
PMID | 1502895
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Chemotherapy, Adjuvant
- Cystadenocarcinoma
(drug therapy, mortality, surgery)
- Female
- Follow-Up Studies
- Humans
- Laparotomy
- Middle Aged
- Ovarian Neoplasms
(drug therapy, mortality, surgery)
- Postoperative Complications
(epidemiology)
- Reoperation
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