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Topical application of natural honey, beeswax and olive oil mixture for atopic dermatitis or psoriasis: partially controlled, single-blinded study.

AbstractOBJECTIVES:
To investigate the effects of honey, olive oil and beeswax mixture on patients with atopic dermatitis (AD) or psoriasis vulgaris (PV).
MATERIALS AND METHODS:
Twenty-one patients with dermatitis and 18 patients with psoriasis were entered for patient-blinded, partially controlled study; 11 patients with dermatitis used topical betamethasone esters and 10 patients with psoriasis used clobetasol propionate. Honey mixture contained honey, beeswax and olive oil (1:1:1). Mixtures A, B, and C contained honey mixture with the corticosteroids ointment in a ratio of 1:1, 2:1, and 3:1 respectively. Patients with dermatitis were subjected to controlled bilateral half-body comparison to evaluate the efficacy of honey mixture against Vaseline, or mixture A against Vaseline-betamethasone esters mixture (1:1) in patients using topical corticosteroid treatment. In patients with psoriasis, the effect of honey mixture was compared with paraffin in an individual right/left-sites comparison, or mixture A against paraffin-clobetasol propionate mixture (1:1) in patients using corticosteroid topical therapy. In dermatitis, body lesions on right or left half-body were assessed for erythema, scaling, lichenification, excoriation, indurations, oozing and itching on a 0-4 points scale. In psoriasis, lesions of selected site were assessed for redness, scaling, thickening and itching, on a 0-4 points scale.
RESULTS:
In honey mixture group, 8/10 patients with dermatitis showed significant improvement after 2 weeks, and 5/11 patients pretreated with betamethasone esters showed no deterioration upon 75% reduction of corticosteroid doses with use of mixture C. In psoriasis, 5/8 patients showed a significant response to honey mixture. In patients using clobetasol propionate, 5/10 patients showed no deterioration upon 75% reduction of corticosteroid doses with use of mixture C.
CONCLUSION:
Honey mixture appears useful in the management of dermatitis and psoriasis vulgaris.
AuthorsNoori S Al-Waili
JournalComplementary therapies in medicine (Complement Ther Med) Vol. 11 Issue 4 Pg. 226-34 (Dec 2003) ISSN: 0965-2299 [Print] Scotland
PMID15022655 (Publication Type: Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article)
Chemical References
  • Anti-Inflammatory Agents
  • Olive Oil
  • Plant Oils
  • Waxes
  • beeswax
  • Betamethasone
  • Clobetasol
Topics
  • Administration, Topical
  • Adolescent
  • Adult
  • Anti-Inflammatory Agents (therapeutic use)
  • Betamethasone (therapeutic use)
  • Child
  • Child, Preschool
  • Clobetasol (analogs & derivatives, therapeutic use)
  • Dermatitis, Atopic (drug therapy)
  • Female
  • Honey
  • Humans
  • Male
  • Middle Aged
  • Olive Oil
  • Plant Oils (therapeutic use)
  • Psoriasis (drug therapy)
  • Single-Blind Method
  • Waxes (therapeutic use)

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