[Intravitreal injection of triamcinolone acetonide for cystoid macular edema resistant to vitreous surgery].

Abstract

PURPOSE:

To report the efficacy of intravitreal injection of triamcinolone acetonide(TA) for cystoid macular edema remaining after vitreous surgery.

METHODS:

Eight eyes of 7 patients aged from 32 to 84 years old were studied. The original diseases that caused macular edema were central retinal vein occlusion in 2 eyes, branch retinal vein occlusion in one eye, Irvine-Gass syndrome in 2 eyes, and diabetic retinopathy in 3 eyes. 4 mg of TA was injected intravitreally and visual acuity and foveal thickness measured by optical coherence tomography(OCT) were evaluated in before and after the surgery.

RESULTS:

Macular edema resolved rapidly after injection of TA in all cases and cysts were extinguished or diminished. The foveal thickness in OCT was reduced significantly from preoperative 495 +/- 116 (mean +/- standard deviation) microns to 267 +/- 117 microns after one week, and 246 +/- 81 microns after one month. The effect persisted for three months. Visual improvement of more than two Snellen lines was seen in 4 eyes. No side effects were observed except a temporary increase of intraocular pressure in one eye.

CONCLUSION:

Intravitreal injection of TA is effective in a short-term for cystoid macular edema remaining after vitrectomy.

• Authors: Makoto Inoue, Norihiro Nagai, Hajime Shinoda, Kei Shinoda, Shizuaki Kitamura, Yoshihisa Oguchi
• Journal: Nippon Ganka Gakkai zasshi (Nippon Ganka Gakkai Zasshi) Vol. 108 Issue 2 Pg. 92-7 (Feb 2004) ISSN: 0029-0203 [Print] Japan
• PMID: 15022431 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Triamcinolone Acetonide

Topics

• Adult
• Aged
• Aged, 80 and over
• Female
• Humans
• Injections, Intralesional
• Macular Edema (drug therapy)
• Male
• Middle Aged
• Postoperative Period
• Triamcinolone Acetonide (administration & dosage, therapeutic use)
• Vitrectomy
• Vitreous Body