Endoscopic detachable mini-loop ligation for treatment of gastroduodenal angiodysplasia: case study of 11 patients with long-term follow-up.

Abstract

BACKGROUND:

Detachable mini-loop ligation is useful for endoscopic management of esophageal varices. This study evaluated the treatment of gastroduodenal angiodysplasia by detachable mini-loop ligation.

METHODS:

Eleven patients (9 women, 2 men; mean age 61 [18] years) with bleeding gastroduodenal angiodysplasia were treated endoscopically by detachable mini-loop ligation. At endoscopy, two patients had actively bleeding lesions. By using a ligating device, a detachable nylon ring was inserted through the accessory channel of an endoscope and opened at the rim of a transparent ligation chamber attached to the tip of the instrument. The angiodysplasia was aspirated into the chamber, and the mini-loop was closed and detached.

OBSERVATIONS:

Initial ligation therapy was successful in all patients without inducing uncontrollable bleeding. In one patient, two mini-loops were applied to the same angiodysplastic lesion. The only significant complication was severe GI bleeding from a duodenal ulcer that developed at the ligation site in one patient. This was successfully treated by endoscopic placement of hemoclips.

CONCLUSIONS:

Detachable mini-loop ligation is an effective and safe modality for endoscopic treatment of bleeding gastroduodenal angiodysplasia.

• Authors: Neven Ljubicić
• Journal: Gastrointestinal endoscopy (Gastrointest Endosc) Vol. 59 Issue 3 Pg. 420-3 (Mar 2004) ISSN: 0016-5107 [Print] United States
• PMID: 14997147 (Publication Type: Journal Article)

Topics

• Adult
• Aged
• Aged, 80 and over
• Angiodysplasia (diagnosis, therapy)
• Duodenoscopy (methods)
• Endoscopy, Gastrointestinal (methods)
• Female
• Follow-Up Studies
• Gastrointestinal Hemorrhage (diagnosis, therapy)
• Gastroscopy (methods)
• Hemostasis, Endoscopic (methods)
• Humans
• Ligation (methods)
• Male
• Middle Aged
• Prospective Studies
• Risk Assessment
• Sampling Studies
• Sensitivity and Specificity
• Time Factors
• Treatment Outcome