Abstract | AIM: METHODS: RE, BE and gastric IM were determined by upper endoscopy. Patients were divided into 2 groups; those with squamocolumnar junction (SCJ) beyond gastroesophageal junction (GEJ) > =3 cm (group A), and those with SCJ beyond GEJ <3 cm (group B). Biopsy specimens were obtained endoscopically from just below the SCJ, gastric antrum along the greater and lesser curvature. Pathological changes and H pylori infection were determined by HE staining, Alcian blue staining and Giemsa staining. RESULTS: The prevalence of H pylori infection was 46.93%. There was no difference in the prevalence between males and females. The prevalence of H pylori infection decreased stepwise significantly from RE grade I to III. There was no difference in the prevalence between the two groups, and between long-segment and short-segment BE. In distal stomach, prevalence of H pylori infection was significantly higher in patients with IM than those without IM. CONCLUSION: There is a protective role of H pylori infection to GERD. There may be no relationship between H pylori infection of stomach and BE. H pylori infection is associated with the development of IM in the distal stomach.
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Authors | Jun Zhang, Xiao-Li Chen, Kang-Min Wang, Xiao-Dan Guo, Ai-Li Zuo, Jun Gong |
Journal | World journal of gastroenterology
(World J Gastroenterol)
Vol. 10
Issue 5
Pg. 672-5
(Mar 01 2004)
ISSN: 1007-9327 [Print] United States |
PMID | 14991936
(Publication Type: Journal Article)
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Topics |
- Barrett Esophagus
(epidemiology, pathology)
- China
(epidemiology)
- Female
- Gastroesophageal Reflux
(epidemiology, pathology)
- Helicobacter Infections
(epidemiology, pathology)
- Helicobacter pylori
- Humans
- Male
- Middle Aged
- Prevalence
- Prospective Studies
- Sex Distribution
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