Fox-Fordyce disease: successful treatment with topical clindamycin in alcoholic propylene glycol solution.

Abstract

We report a 66-year-old woman with a 3-year history of intensely pruritic follicular papules in the axillar, pubic and inguinal areas. Previous treatment with topical fusidic acid and gentamicin sulfate was ineffective. The clinical and histological examination was consistent with Fox-Fordyce disease. Application of clindamycin in an alcoholic propylene glycol solution led to the clearing of the lesions within 1 month. Nine months later, the treatment was stopped, and no recurrence was observed.

• Authors: R Feldmann, I Masouyé, P Chavaz, J H Saurat
• Journal: Dermatology (Basel, Switzerland) (Dermatology) Vol. 184 Issue 4 Pg. 310-3 ( 1992) ISSN: 1018-8665 [Print] Switzerland
• PMID: 1498406 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Drug Combinations
• Propylene Glycols
• Solutions
• Clindamycin
• Propylene Glycol
• 1-Propanol

Topics

• 1-Propanol (administration & dosage, therapeutic use)
• Administration, Topical
• Aged
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage, therapeutic use)
• Clindamycin (administration & dosage, therapeutic use)
• Drug Combinations
• Female
• Fox-Fordyce Disease (drug therapy)
• Humans
• Propylene Glycol
• Propylene Glycols (administration & dosage, therapeutic use)
• Solutions