Therapeutic effect of transcatheter arterial chemoembolization and percutaneous injection of acetic acids on primary liver cancer.

Abstract

BACKGROUND:

The resection rate of primary liver tumor in China is only about 20%. A lot of patients with moderate and advanced liver tumor may lose the chance of operation. The objective of present research was to study the efficacy of transcatheter arterial chemoembolization (TACE) combined with percutaneous injection of chemical agents and acetic acids in the treatment of patients with primary liver cancer (PLC).

METHODS:

Thirty-three patients with middle and advanced stage of PLC were divided into two groups: percutaneous injection of chemical agents and acetic acids (15 patients, group A) and TACE (18 patients, group B).

RESULTS:

Tumor diameter and serum AFP level reduced to 86.6% and 83.3% in group A, and 55.5% and 40% in group B, respectively. There was significant difference between the two groups (P<0.01). The 1, 2, 3, 4-year survival rates of group A were 96.7%, 86.6%, 51.3%, 33.3%, respectively and in group B were 66.7%, 44.4%, 16.7%, 0%, respectively (P<0.01).

CONCLUSION:

TACE combined with percutaneous injection of chemical agents and acetic acids is efficacious to increase the survival rate of patients with PLC.

• Authors: Hong-Bin Chen, Yue Huang, Dong-Ling Dai, Xia Zhang, Zhong-Wen Huang, Qi-Kai Zhang, Hui-Hua Wang, Jun-Su Zhang, Ge Pan
• Journal: Hepatobiliary & pancreatic diseases international : HBPD INT (Hepatobiliary Pancreat Dis Int) Vol. 3 Issue 1 Pg. 55-7 (Feb 2004) ISSN: 1499-3872 [Print] Singapore
• PMID: 14969838 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Acetates

Topics

• Acetates (administration & dosage)
• Adult
• Aged
• Antineoplastic Combined Chemotherapy Protocols (administration & dosage)
• Carcinoma, Hepatocellular (mortality, pathology, therapy)
• Catheterization
• Chemoembolization, Therapeutic (methods)
• Combined Modality Therapy
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Female
• Follow-Up Studies
• Hepatic Artery
• Humans
• Injections, Subcutaneous
• Liver Neoplasms (mortality, pathology, therapy)
• Male
• Middle Aged
• Probability
• Prospective Studies
• Risk Assessment
• Survival Analysis
• Treatment Outcome