[Effect of Corynebacterium parvum on the immune response in guinea pigs. II. Passive transfer of enhanced anamnestic response and delayed hypersensitivity observed after treatment with Corynebacterium parvum].

Abstract

After intradermal immunization with a mixture of Corynebacterium parvum (C. parvum) and ovalbumin guinea pigs show a markedly increased anamnestic response to an intradermal booster of ovalbumin as compared to controls treated with ovalbumin only. At the same time a reaction of delayed type hypersensitivity is observed in the treated animals, but not in controls. The enhanced anamnestic response as well as the posivitive skin reaction were transferred to strain 2 histocompatible guinea pigs by peripheral blood leukocytes as well as by peritoneal exudate cells. Passive transfer was not obtained after prior irradiation of donor animals.

• Authors: B Halpern, S Gauthier-Rahman, D Besluau
• Journal: Comptes rendus des seances de la Societe de biologie et de ses filiales (C R Seances Soc Biol Fil) Vol. 171 Issue 6 Pg. 1209-16 ( 1977) ISSN: 0037-9026 [Print] France
• Vernacular Title: Effet du Corynebacterium parvum sur la réponse immune du Cobaye. II. Transfert passif de la réponse anamnestique amplifiée et de l'hypersensibilité retardée obtenue après traitement par le Corynebacterium parvum.
• PMID: 148949 (Publication Type: English Abstract, Journal Article)

Chemical References

• Antibodies
• Antibodies, Bacterial
• Ovalbumin

Topics

• Animals
• Antibodies (analysis)
• Antibodies, Bacterial (analysis)
• Antibody Formation
• Ascitic Fluid (cytology)
• Blood Transfusion
• Guinea Pigs
• Hypersensitivity, Delayed
• Immunization, Passive
• Lymphocytes (immunology)
• Ovalbumin (immunology)
• Propionibacterium acnes (immunology)
• Radiation Effects