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Pemphigoid gestationis--response to chemical oophorectomy with goserelin.

Abstract
A 46-year-old caucasian female presented in January 1991 with a 17-year history of severe pemphigoid gestationis. She had been on systemic steroids for 10 years since her last pregnancy in 1981 and required doses of 20-80 mg prednisolone daily to control her disease. A chemical oophorectomy was induced using a new luteinizing hormone releasing hormone (LHRH) analogue known as goserelin. A complete remission occurred within 6 months of initiating this treatment and the systemic steroids were discontinued.
AuthorsM P Garvey, S E Handfield-Jones, M M Black
JournalClinical and experimental dermatology (Clin Exp Dermatol) Vol. 17 Issue 6 Pg. 443-5 (Nov 1992) ISSN: 0307-6938 [Print] England
PMID1486714 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Goserelin
Topics
  • Female
  • Goserelin (therapeutic use)
  • Humans
  • Middle Aged
  • Ovariectomy (methods)
  • Pemphigoid, Bullous (drug therapy, pathology)

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