Abstract |
This is a preliminary study of the treatment of 36 patients with Peyronie's disease who received tamoxifen 20 mg twice daily for 3 months. An improvement occurred in 16 of 20 patients with penile pain, in 11 of 31 patients with an erectile deformity and 12 of 35 patients had a plaque shrinkage of at least 1 cm. Some improvement occurred in 6 of the 8 patients with a histologically confirmed inflammatory infiltrate of the plaque but not in any of the 4 patients without an infiltrate. The inflammatory infiltrate was found in patients in whom the duration of the disease was less than 4 months.
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Authors | D J Ralph, M D Brooks, G F Bottazzo, J P Pryor |
Journal | British journal of urology
(Br J Urol)
Vol. 70
Issue 6
Pg. 648-51
(Dec 1992)
ISSN: 0007-1331 [Print] England |
PMID | 1486392
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Aged
- Humans
- Male
- Middle Aged
- Penile Induration
(drug therapy, pathology)
- Penis
(pathology)
- Tamoxifen
(therapeutic use)
- Time Factors
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