[Benzidamine in the topical treatment of vaginitis caused by Gardnerella vaginalis].

Abstract

The present clinical trial has been carried out in order to evaluate the efficacy of benzydamine in treatment of vaginitis caused by Gardnerella vaginalis. Fifty women affected by this specific pathology have been submitted to topical treatment with 0.5% benzydamine vaginal cream. The treatment has been carried out for 9 consecutive days using a local application of benzydamine twice a day. The clinical result was evaluated after 12 and 60 days. The following parameters were taken into consideration: symptoms (leucorrhea, itching, burning), clinical signs (oedema, hyperemia, vaginal secretion), instrumental data (pH, colposcopy, sniff test) and microbiological findings (searching of clue cells, Lactobacillus and Gardnerella vaginalis). At the first check point after 12 days 84% of patients have been considered healed; at the second check the percentage of healing rose to 92%. Therefore benzydamine was considered highly effective in 92% of vaginitis caused by Gardnerella vaginalis.

• Authors: P L Bracco, G L Bracco, A M Vassallo
• Journal: Minerva ginecologica (Minerva Ginecol) Vol. 44 Issue 11 Pg. 573-84 (Nov 1992) ISSN: 0026-4784 [Print] Italy
• Vernacular Title: La benzidamina nel trattamento topico della vaginite da Gardnerella vaginalis.
• PMID: 1480306 (Publication Type: English Abstract, Journal Article)

Chemical References

• Benzydamine

Topics

• Administration, Topical
• Benzydamine (administration & dosage)
• Female
• Gardnerella vaginalis (isolation & purification)
• Humans
• Vaginosis, Bacterial (drug therapy, microbiology)