Therapeutic efficacy of laparoscopic cholecystectomy in the treatment of biliary dyskinesia.

Abstract

BACKGROUND:

The outcome of laparoscopic cholecystectomy for patients who present with "classic" biliary colic without evidence of cholelithiasis or acute inflammation (biliary dyskinesia) is not well documented. This study evaluates whether a cholecystokinin dimethyl iminodiacetic acid (CCK-HIDA) scan can predict relief of symptoms in this group of patients.

METHODS:

Patients who underwent laparoscopic cholecystectomy after a normal ultrasound and with an abnormal dimethyl iminodiacetic acid scan were retrospectively reviewed. Symptomatic improvement was correlated with degree of dyskinesia, histologic findings, sex, and age.

RESULTS:

One hundred seventy-six patients were studied and 69% were available for followup at a mean interval of 16 months. One hundred fourteen patients (94%) had complete or partial relief of symptoms. No correlation was found between degree of relief and degree of impaired ejection (31% to 50% versus <30%), the histologic findings, sex, or age.

CONCLUSIONS:

Abnormal cholecystokinin dimethyl iminodiacetic acid scan effectively predicts relief of symptoms in patients undergoing laparoscopic cholecystectomy for biliary dyskinesia.

• Authors: Nilesh A Patel, Jason J Lamb, Nancy J Hogle, Dennis L Fowler
• Journal: American journal of surgery (Am J Surg) Vol. 187 Issue 2 Pg. 209-12 (Feb 2004) ISSN: 0002-9610 [Print] United States
• PMID: 14769306 (Publication Type: Journal Article)

Chemical References

• Gastrointestinal Agents
• Imino Acids
• Radiopharmaceuticals
• Cholecystokinin
• iminodiacetic acid

Topics

• Biliary Dyskinesia (diagnostic imaging, surgery)
• Cholecystectomy, Laparoscopic
• Cholecystokinin
• Female
• Gastrointestinal Agents
• Humans
• Imino Acids
• Male
• Radionuclide Imaging
• Radiopharmaceuticals
• Retrospective Studies
• Treatment Outcome