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[Role of calcium and magnesium ions in cerebrospinal fluid in alcoholic-traumatic coma].

Abstract
The goal of investigation was to determine the role of calcium and magnesium ions in the cerebrospinal fluid in ethylic-traumatic coma. We measured the level of calcium in the cerebrospinal fluid within simple photometric test and the magnesium level within xylidyl blue photometric test. We found a high mortality in patients with high level of calcium in cerebrospinal fluid and low level of magnesium in cerebrospinal fluid. At patients with ethylic-traumatic coma high levels of calcium in cerebrospinal fluid are caused by the excitatory amino acids cascade and increased of hematoencephalic barrier permeability. Decreased levels of magnesium in cerebrospinal fluid are associated with convulsions and a poor prognosis of the patients. These analyses are very important for establishment of prognosis in patients with ethylic-traumatic coma.
AuthorsCristina Bologa, M Rusu, N Ianovici, C Tetraru, J Hurjui, O Petriş, Cătălina Lionte
JournalRevista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi (Rev Med Chir Soc Med Nat Iasi) 2003 Oct-Dec Vol. 107 Issue 4 Pg. 809-12 ISSN: 0048-7848 [Print] Romania
Vernacular TitleRolul determinării ionilor de calciu şi magneziu în LCR în coma etilico-traumatică.
PMID14756024 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Biomarkers
  • Magnesium
  • Calcium
Topics
  • Adult
  • Alcoholism (cerebrospinal fluid, complications)
  • Biomarkers (cerebrospinal fluid)
  • Calcium (cerebrospinal fluid)
  • Cerebrospinal Fluid (metabolism)
  • Coma, Post-Head Injury (cerebrospinal fluid, etiology, mortality)
  • Female
  • Humans
  • Magnesium (cerebrospinal fluid)
  • Male
  • Middle Aged
  • Prognosis

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