Abstract | PURPOSE: MATERIALS: RESULTS: Out of 232 patients, 93 have an APS (76 primary APS, 17 secondary APS). Thrombosis occurred 138 times in APS patients. Of 139 patients without APS, 95 have an auto- immune disease, 28 have an isolated prolonged KCT and 16 an evolutive neoplasia. LA seems to be the best marker of APS. On the other hand aCL IgG and M, anti-beta2-GP1 IgM titers are significantly higher in patients without APS but with HG. CONCLUSION: Those results suggest that biological APS diagnosis should be carefully performed in patients with HG. In this case, other additional risk factors must be considered for the etiological diagnosis of thrombosis.
|
Authors | M Lambert, A-L Fauchais, S Dubucquoi, D Launay, C Caron, L Prin, E Hachulla, P-Y Hatron, B Devulder |
Journal | La Revue de medecine interne
(Rev Med Interne)
Vol. 25
Issue 2
Pg. 111-4
(Feb 2004)
ISSN: 0248-8663 [Print] France |
Vernacular Title | Etude de l'influence d'une hypergammaglobulinémie sur le titre des anticorps antiphospholipides. |
PMID | 14744640
(Publication Type: English Abstract, Journal Article)
|
Chemical References |
- Antibodies, Antiphospholipid
- Biomarkers
|
Topics |
- Adult
- Antibodies, Antiphospholipid
(blood)
- Biomarkers
(analysis)
- False Positive Reactions
- Female
- Humans
- Hypergammaglobulinemia
(complications, diagnosis)
- Male
- Middle Aged
- Retrospective Studies
- Sensitivity and Specificity
- Thrombosis
|