Abstract |
The goal of the study was to assess the prognostic value of ultrasound finding of fetal cystic hygromas. Thirty cases of septated cystic hygromas were diagnosed at 10-15 weeks gestation by transabdominal ultrasound and followed through pregnancy. The rate of abnormal karyotype was found to be 61% and the global rate of unfavorable outcome, independently of karyotype result, as high as 96%. These data suggest that cautious genetic counselling should be offered when such cystic hygromas are noticed during the first 15 weeks of gestation, even with a normal karyotype.
|
Authors | A Paoloni-Giacobino, D Extermann, Ph Extermann, S Y Dahoun |
Journal | Genetic counseling (Geneva, Switzerland)
(Genet Couns)
Vol. 14
Issue 4
Pg. 413-8
( 2003)
ISSN: 1015-8146 [Print] Switzerland |
PMID | 14738115
(Publication Type: Journal Article)
|
Topics |
- Adult
- Chromosome Aberrations
(statistics & numerical data)
- Congenital Abnormalities
(epidemiology)
- Female
- Genetic Counseling
- Humans
- Karyotyping
- Lymphangioma, Cystic
(diagnostic imaging)
- Pregnancy
- Pregnancy Outcome
- Switzerland
(epidemiology)
- Ultrasonography, Prenatal
|