Abstract | PURPOSE: OBJECTIVE: The aim of the study was to evaluate the activation state of circulating platelets in patients suffering from AEDS. MATERIAL AND METHODS: In vivo platelet activity was assessed by measuring plasma level of PF4 ( enzyme-linked immunoassay method) in 9 males AEDS patients and 11 healthy, nonatopic subjects. RESULTS: Plasma PF4 was significantly increased (p < 0.05) in AEDS (31.88 +/- 20.48 IU/ml) patients compared with control subjects (2.95 +/- 0.6 IU/ml). CONCLUSIONS: This result suggests that patients with AEDS may have increased in vivo platelet activation expressed by PF4 release. The aim of the study was to evaluate the activation state of circulating platelets in patients suffering from AEDS.
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Authors | A Kasperska-Zajac, B Rogala, M Nowakowski |
Journal | Roczniki Akademii Medycznej w Bialymstoku (1995)
(Rocz Akad Med Bialymst)
Vol. 48
Pg. 128-30
( 2003)
Poland |
PMID | 14737958
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Platelet Factor 4
- Immunoglobulin E
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Topics |
- Adult
- Dermatitis, Atopic
(blood, immunology)
- Humans
- Immunoglobulin E
(analysis, immunology)
- Male
- Platelet Activation
(immunology)
- Platelet Factor 4
(analysis, immunology)
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