Abstract | INTRODUCTION: PATIENTS AND METHODS: Study in a single center of 59 patients having consulted for urticaria that had progressed for more than six weeks and without precise etiology. An autologous serum test was conducted and anti-thyroid autoantibodies were searched for in the serum stored after the test. RESULTS: Out of 59 patients, 51 had an interpretable autologous serum test and 57 underwent research for anti-thyroid antibodies. Twelve patients out 57 (21 p.cent) exhibited one or more types of positive (n=10) or borderline (n=2) anti-thyroid antibodies, and eight out of 12 (66.6 p.cent) had a known thyroid disease before the onset of urticaria. The systematic blood test permitted the discovery of 4 cases of unknown anti-thyroid antibodies. The symptoms regressed in two of these patients without any specific treatment, one patient was treated with L thyroxin for hyperthyroidism without any improvement in the symptoms and one other patient had normal thyroid function. Among these 12 patients, 11 underwent autologous serum tests, but only 3 of them exhibited clearly positive results and one was doubtful. CONCLUSIONS: Within the limits of this study, we found a 21 p.cent rate of patients with chronic urticaria exhibiting one or more anti-thyroid antibodies. The positivity of the autologous serum test does not appear to be related with autoimmune thyroid disorders.
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Authors | C Vermeulen, P Mathelier-Fusade, A-M Rouquette, O Bayrou, C Pecquet, F Leynadier |
Journal | Annales de dermatologie et de venereologie
(Ann Dermatol Venereol)
Vol. 130
Issue 12 Pt 1
Pg. 1115-8
(Dec 2003)
ISSN: 0151-9638 [Print] France |
Vernacular Title | Urticaire chronique, thyroïdite auto-immune et test au sérum autologue. |
PMID | 14724513
(Publication Type: English Abstract, Journal Article)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Autoantibodies
(blood)
- Child
- Chronic Disease
- Female
- Humans
- Male
- Middle Aged
- Thyroiditis, Autoimmune
(blood, diagnosis)
- Urticaria
(blood, diagnosis)
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