HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Chronic urticaria, thyroiditis and autologous serum test].

AbstractINTRODUCTION:
The autoimmune nature of certain forms of chronic urticaria remains debatable. Aim of the study. To find a correlation in terms of autoimmune pattern between chronic urticaria and thyroiditis using the autologous serum test and the search for anti-thyroid antibodies.
PATIENTS AND METHODS:
Study in a single center of 59 patients having consulted for urticaria that had progressed for more than six weeks and without precise etiology. An autologous serum test was conducted and anti-thyroid autoantibodies were searched for in the serum stored after the test.
RESULTS:
Out of 59 patients, 51 had an interpretable autologous serum test and 57 underwent research for anti-thyroid antibodies. Twelve patients out 57 (21 p.cent) exhibited one or more types of positive (n=10) or borderline (n=2) anti-thyroid antibodies, and eight out of 12 (66.6 p.cent) had a known thyroid disease before the onset of urticaria. The systematic blood test permitted the discovery of 4 cases of unknown anti-thyroid antibodies. The symptoms regressed in two of these patients without any specific treatment, one patient was treated with L thyroxin for hyperthyroidism without any improvement in the symptoms and one other patient had normal thyroid function. Among these 12 patients, 11 underwent autologous serum tests, but only 3 of them exhibited clearly positive results and one was doubtful.
CONCLUSIONS:
Within the limits of this study, we found a 21 p.cent rate of patients with chronic urticaria exhibiting one or more anti-thyroid antibodies. The positivity of the autologous serum test does not appear to be related with autoimmune thyroid disorders.
AuthorsC Vermeulen, P Mathelier-Fusade, A-M Rouquette, O Bayrou, C Pecquet, F Leynadier
JournalAnnales de dermatologie et de venereologie (Ann Dermatol Venereol) Vol. 130 Issue 12 Pt 1 Pg. 1115-8 (Dec 2003) ISSN: 0151-9638 [Print] France
Vernacular TitleUrticaire chronique, thyroïdite auto-immune et test au sérum autologue.
PMID14724513 (Publication Type: English Abstract, Journal Article)
Chemical References
  • Autoantibodies
Topics
  • Adolescent
  • Adult
  • Aged
  • Autoantibodies (blood)
  • Child
  • Chronic Disease
  • Female
  • Humans
  • Male
  • Middle Aged
  • Thyroiditis, Autoimmune (blood, diagnosis)
  • Urticaria (blood, diagnosis)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: