Abstract | OBJECTIVE: STUDY DESIGN: One hundred ninety-five infants of women with gestational diabetes mellitus and 220 infants of women with normal glucose tolerance had anthropometric measurements and total body electrical conductivity body composition evaluations at birth. Parental demographic, anthropometric, medical and family history data, and diagnostic glucose values were used to develop a stepwise regression model that related to fetal growth and body composition. RESULTS: CONCLUSION: Infants of women with gestational diabetes mellitus, even when they are average weight for gestational age, have increased body fat compared with infants of women with normal glucose tolerance. Maternal fasting glucose level was the strongest predictor of fat mass in infants of women with gestational diabetes mellitus. This increase in body fat may be a significant risk factor for obesity in early childhood and possibly in later life.
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Authors | Patrick M Catalano, Alicia Thomas, Larraine Huston-Presley, Saeid B Amini |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 189
Issue 6
Pg. 1698-704
(Dec 2003)
ISSN: 0002-9378 [Print] United States |
PMID | 14710101
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
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Chemical References |
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Topics |
- Adipose Tissue
(metabolism)
- Adult
- Biomarkers
(analysis)
- Birth Weight
- Body Mass Index
- Case-Control Studies
- Diabetes, Gestational
(complications, diagnosis)
- Embryonic and Fetal Development
(physiology)
- Female
- Fetal Macrosomia
(diagnosis, etiology)
- Gestational Age
- Glucose Tolerance Test
- Humans
- Infant, Newborn
- Pregnancy
- Pregnancy Outcome
- Probability
- Reference Values
- Risk Assessment
- Sensitivity and Specificity
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