Abstract |
No doubt, schistosomiasis tops all the endemic parasitic diseases world-wide particularly in Egypt. This study evaluated the efficacy of Mirazid (Commiphora molmol) in the treatment of parasitologically and clinically and ultrasonography confirmed cases of schistosomiasis haematobium in Tatoon village. A sum of 70 out of 885 individuals of both sexes (>15 to 60 years old) screened for S. haematobium infection were selected. They had light infection (1-10 eggs/10 ml.), moderate infection (10-100 eggs/10 ml.) and heavy infection (>100/10 ml.). They were subjected to urine and stool analysis, renal function tests, clinical examination and abdomino-pelvic ultrasound. They were treated with Mirazid as 10 mgm/Kg. However, eight of them were unable to swallow the drug. Out of the 62 schistosomiasis haematobium patients, 57 (91.9%) were cured after two months follow up and the cure rate reached 59 (95.2%) on the 3rd month post- Mirazid treatment. The cure result was evaluated clinically, parasitologically and ultrasonographically. So, Mirazid in a dose of two capsules (600 mgm) on an empty stomach before breakfast for six successive days proved to be very effective and safe in the treatment of schistosomiasis haematobium.
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Authors | Mohammad A El Baz, Tosson A Morsy, Mahmoud M El Bandary, Saad M Motawea |
Journal | Journal of the Egyptian Society of Parasitology
(J Egypt Soc Parasitol)
Vol. 33
Issue 3
Pg. 761-76
(Dec 2003)
ISSN: 1110-0583 [Print] Egypt |
PMID | 14708852
(Publication Type: Journal Article)
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Chemical References |
- Plant Extracts
- Schistosomicides
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Topics |
- Adolescent
- Adult
- Animals
- Commiphora
(chemistry)
- Dose-Response Relationship, Drug
- Egypt
- Feces
(parasitology)
- Female
- Humans
- Male
- Middle Aged
- Phytotherapy
- Plant Extracts
(pharmacology, therapeutic use)
- Schistosoma haematobium
(drug effects)
- Schistosomiasis haematobia
(diagnostic imaging, drug therapy, prevention & control)
- Schistosomicides
(pharmacology, therapeutic use)
- Treatment Outcome
- Ultrasonography
- Urine
(parasitology)
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