Protein kinase C inhibition and diabetic retinopathy: a shot in the dark at translational research.

Abstract

TRANSLATIONAL RESEARCH IN PRACTICE: a PKC-beta inhibitor for diabetic retinopathy

• Authors: R Donnelly, I Idris, J V Forrester
• Journal: The British journal of ophthalmology (Br J Ophthalmol) Vol. 88 Issue 1 Pg. 145-51 (Jan 2004) ISSN: 0007-1161 [Print] England
• PMID: 14693793 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Enzyme Inhibitors
• Indoles
• Maleimides
• Vascular Endothelial Growth Factor A
• ruboxistaurin
• Protein Kinase C

Topics

• Diabetic Retinopathy (drug therapy, enzymology)
• Enzyme Activation
• Enzyme Inhibitors (therapeutic use)
• Humans
• Indoles (therapeutic use)
• Maleimides (therapeutic use)
• Protein Kinase C (antagonists & inhibitors, physiology)
• Randomized Controlled Trials as Topic
• Vascular Endothelial Growth Factor A (physiology)