Reversal of neurological deficit with naloxone: an additional report.

Abstract

We report the repeated improvement in neurological function following naloxone administration in a patient who developed acute hemiplegia after an intracranial neurological procedure. The mechanisms responsible for the neurological deficit and for its reversal by naloxone are discussed. A review of the literature suggests that the beneficial effect of naloxone can result from an improvement in haemodynamic status or from metabolic effects that could be favorable during cerebral ischaemia.

• Authors: P Hans, J F Brichant, E Longerstay, F Damas, J M Remacle
• Journal: Intensive care medicine (Intensive Care Med) Vol. 18 Issue 6 Pg. 362-3 ( 1992) ISSN: 0342-4642 [Print] United States
• PMID: 1469163 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Naloxone
• Sufentanil

Topics

• Arachnoid Cysts (surgery)
• Female
• Hemiplegia (diagnostic imaging, drug therapy, etiology)
• Humans
• Middle Aged
• Naloxone (administration & dosage, pharmacology, therapeutic use)
• Postoperative Complications (diagnostic imaging, drug therapy, etiology)
• Sufentanil (adverse effects)
• Tomography, X-Ray Computed