Abstract | BACKGROUND/AIMS: METHODS: RESULTS: At 3 months on enalapril, albuminuria decreased in all patients (1,042 vs 629 mg per 24 h, p < 0.05). The median reduction of albuminuria was 43% (range: 4 - 72%, p < 0.05). Urinary excretion of alpha1 microglobulin remained constant. Systolic blood pressure decreased from median 110 - 100 mmHg (p < 0.05), while diastolic blood pressure remained stable (median 60 mmHg). Creatinine clearance decreased from median 48 - 45 ml/min/1.73 m2 (p < 0.05) and returned to previous values after discontinuation of enalapril. CONCLUSION:
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Authors | E Levtchenko, H Blom, M Wilmer, L van den Heuvel, L Monnens |
Journal | Clinical nephrology
(Clin Nephrol)
Vol. 60
Issue 6
Pg. 386-9
(Dec 2003)
ISSN: 0301-0430 [Print] Germany |
PMID | 14690254
(Publication Type: Journal Article)
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Chemical References |
- Angiotensin-Converting Enzyme Inhibitors
- Enalapril
- Creatinine
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Topics |
- Albuminuria
(drug therapy, etiology)
- Angiotensin-Converting Enzyme Inhibitors
(therapeutic use)
- Blood Pressure
- Child
- Child, Preschool
- Creatinine
(blood, urine)
- Cystinosis
(complications)
- Enalapril
(therapeutic use)
- Humans
- Proteinuria
(complications)
- Statistics, Nonparametric
- Treatment Outcome
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