Reproducible induction of atrioventricular nodal reentrant tachycardia with adenosine triphosphate.

Abstract

A 29-year-old woman was referred for electrophysiological testing and radiofrequency ablation because of repeated episodes of palpitation of a 8-year duration. The 12-lead ECG during palpitations showed narrow QRS tachycardia at a rate of 160 beats/min. Dual AVN physiology according to electrophysiological criteria was not shown by single atrial extrastimulation and the tachycardia could not be induced. Slow/fast atrioventricular nodal reentrant tachycardia (AVNRT) was induced once by double atrial extrastimuli, but it was not reproducible. However, intravenous bolus injection of adenosine triphosphate (12.5 mg) during sinus rhythm led to reproducible initiation of slow/fast AVNRT.

• Authors: Yasuo Okumura, Ichiro Watanabe, Naohiro Oshikawa, Riko Masaki, Kimie Ohkubo, Takeshi Yamada, Tatsuya Kofune, Rie Wakita, Yasuhiro Takagi, Kenichi Hashimoto, Satoshi Saito, Yukio Ozawa, Katsuo Kanmatsuse
• Journal: Pacing and clinical electrophysiology : PACE (Pacing Clin Electrophysiol) Vol. 26 Issue 12 Pg. 2321-3 (Dec 2003) ISSN: 0147-8389 [Print] United States
• PMID: 14675021 (Publication Type: Case Reports, Journal Article)

Chemical References

• Adenosine Triphosphate

Topics

• Adenosine Triphosphate
• Adult
• Electrocardiography
• Female
• Humans
• Tachycardia, Atrioventricular Nodal Reentry (chemically induced, diagnosis)