[A successful treatment with micafungin of candidemia due to Candida krusei].

Abstract

We report a case of candidemia due to Candida krusei after subarachinoid hemorrhage. A 51 year-old male patient consulted us for high fever and increase of CRP 10 days post operation against subarachinoid hemorrhage. There was a temporary decrease in the CRP after administration of ceftazidime (CAZ) but it again when treatment with CAZ was stopped. Because of detected Candida sp. by blood culture, fluconazole was administered i.v. for 5 days, but C. krusei was positive during the treatment. Therefore, fluconazole was replaced with micafungin. The patient became better after the administration with micafungin for 14 days without side effect. Micafungin is effective against candidemia due to C. krusei.

• Authors: Masato Nonoyama, Hikaru Kume, Ken Kumagai, Kazui Souma, Keisuke Sunakawa
• Journal: Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases (Kansenshogaku Zasshi) Vol. 77 Issue 11 Pg. 982-5 (Nov 2003) ISSN: 0387-5911 [Print] Japan
• PMID: 14672012 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antifungal Agents
• Echinocandins
• Lipopeptides
• Lipoproteins
• Peptides, Cyclic
• Micafungin

Topics

• Antifungal Agents (therapeutic use)
• Candidiasis (drug therapy)
• Echinocandins
• Fungemia (drug therapy)
• Humans
• Lipopeptides
• Lipoproteins (therapeutic use)
• Male
• Micafungin
• Middle Aged
• Peptides, Cyclic (therapeutic use)