Abstract | UNLABELLED: MATERIALS AND METHODS: 67 women with single pregnancy between 24-36 week of gestation after PPROM were included into the study group. All women were managed expectantly ( tocolysis, antibiotics, steroids, intravaginal chemiotherapeutics, bed rest), maternal and fetal (KTG, USG) vital signs were monitored every day. EG, CRP and WBC blood test were performed every day. Histopathologic examinations of all placentas were performed for chorioamnionitis confirmation or exclusion. Normal range for EG--88 micrograms/l, CRP--15 micrograms/l, WBC--15 x 10(9). RESULTS: The usefulness of granulocyte elastase plasma serial determination as biochemical marker of chorioamnionitis in cases of PPROM was confirmed: sensitivity--100%, specificity--33%, PPV--64.9%, NPV--100% in comparison with CRP: sensitivity--27%, specificity--80%, PPV--62.5%, NPV--47% and white blood cell count: sensitivity--27%, specificity--66.7%, PPV--50%, NPV-42.5%. CONCLUSIONS:
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Authors | E Małgorzata Bańkowska, Jerzy Leibschang, Adriana Pawłowska |
Journal | Ginekologia polska
(Ginekol Pol)
Vol. 74
Issue 10
Pg. 1037-43
(Oct 2003)
ISSN: 0017-0011 [Print] Poland |
Vernacular Title | Ocena przydatności oznaczania elastazy granulocytarnej, białka C--reaktywnego i całkowitej liczby krwinek białych w rozpoznaniu zakazenia wewnatrzmacicznego u ciezarnych po przedwczesnym peknieciu błon płodowych (PROM). |
PMID | 14669391
(Publication Type: Comparative Study, Evaluation Study, Journal Article)
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Chemical References |
- Biomarkers
- C-Reactive Protein
- Leukocyte Elastase
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Topics |
- Adult
- Biomarkers
(blood)
- C-Reactive Protein
(metabolism)
- Chorioamnionitis
(diagnosis, etiology)
- Female
- Fetal Membranes, Premature Rupture
(blood, complications)
- Humans
- Leukocyte Count
- Leukocyte Elastase
(blood)
- Leukocytes
- Poland
- Predictive Value of Tests
- Pregnancy
- Sensitivity and Specificity
- Time Factors
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