Abstract | OBJECTIVE: METHODS: Adopting the randomized double-blinded method, the effect of adding NYG to 30 patients with Parkinsonism in the treated group, who already received anti- Parkinsonism treatment but showing decreased response to Medopa and Artane and with obvious adverse reaction, was observed and controlled by 30 patients treated by adding placebo. RESULTS: The total effective rate in the treated group and the control group was 86.7% and 56.7% respectively, the total syndrome improving rate was 90% and 56.7% respectively and the toxicity attenuating rate 90% and 43.3% respectively, comparison between the two groups showed significant difference (P < 0.05 or P < 0.01). NYG also showed markedly effective in reducing the adverse reactions of Medopa and Artane on digestive, neuro-psychiatric and cardiovascular system. CONCLUSION: NYG has obvious efficacy enhancing and toxicity attenuating effects caused by the anti- Parkinsonism treatment with Medopa and Artane.
|
Authors | Xue-jun Hu, Xiao-su Yang, Xu-guang Yang |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 23
Issue 11
Pg. 811-4
(Nov 2003)
ISSN: 1003-5370 [Print] China |
PMID | 14666759
(Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Antiparkinson Agents
- Drugs, Chinese Herbal
- Levodopa
|
Topics |
- Aged
- Antiparkinson Agents
(therapeutic use)
- Double-Blind Method
- Drug Therapy, Combination
- Drugs, Chinese Herbal
(therapeutic use)
- Female
- Humans
- Levodopa
(therapeutic use)
- Male
- Middle Aged
- Parkinson Disease
(drug therapy)
- Phytotherapy
|