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Acute verbal dyspraxia, a rare presentation in multiple sclerosis: a case report with MRI localization.

Abstract
Cortical speech disorders rarely occur in multiple sclerosis (MS). We report a patient with relapsing-remitting MS, who presented with acute verbal dyspraxia. Magnetic resonance imaging (MRI) demonstrated an acute T2/Flair hyperintense, primarily white matter lesion underlying the middle third of the inferior frontal gyrus. The verbal dyspraxia cleared beginning 48 hours after the initiation of iv dexamethasone. Follow-up MRI demonstrated qualitative and quantitative diminution of the hyperintensity. This is the first report of a clinically definite MS patient with acute verbal dyspraxia. Moreover, there was a suggestive localization of verbal praxis to Brodmann areas 44/45.
AuthorsStephen L Jaffe, Michael F Glabus, Roger E Kelley, Alireza Minagar
JournalMultiple sclerosis (Houndmills, Basingstoke, England) (Mult Scler) Vol. 9 Issue 6 Pg. 630-2 (Dec 2003) ISSN: 1352-4585 [Print] England
PMID14664479 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Glucocorticoids
  • Dexamethasone
Topics
  • Acute Disease
  • Adult
  • Apraxias (drug therapy, etiology, pathology)
  • Brain (pathology)
  • Dexamethasone (therapeutic use)
  • Glucocorticoids (therapeutic use)
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Multiple Sclerosis, Relapsing-Remitting (complications, drug therapy, pathology)

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