Abstract |
Cortical speech disorders rarely occur in multiple sclerosis (MS). We report a patient with relapsing-remitting MS, who presented with acute verbal dyspraxia. Magnetic resonance imaging (MRI) demonstrated an acute T2/Flair hyperintense, primarily white matter lesion underlying the middle third of the inferior frontal gyrus. The verbal dyspraxia cleared beginning 48 hours after the initiation of iv dexamethasone. Follow-up MRI demonstrated qualitative and quantitative diminution of the hyperintensity. This is the first report of a clinically definite MS patient with acute verbal dyspraxia. Moreover, there was a suggestive localization of verbal praxis to Brodmann areas 44/45.
|
Authors | Stephen L Jaffe, Michael F Glabus, Roger E Kelley, Alireza Minagar |
Journal | Multiple sclerosis (Houndmills, Basingstoke, England)
(Mult Scler)
Vol. 9
Issue 6
Pg. 630-2
(Dec 2003)
ISSN: 1352-4585 [Print] England |
PMID | 14664479
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Glucocorticoids
- Dexamethasone
|
Topics |
- Acute Disease
- Adult
- Apraxias
(drug therapy, etiology, pathology)
- Brain
(pathology)
- Dexamethasone
(therapeutic use)
- Glucocorticoids
(therapeutic use)
- Humans
- Magnetic Resonance Imaging
- Male
- Multiple Sclerosis, Relapsing-Remitting
(complications, drug therapy, pathology)
|