Topical calcipotriol ointment in the treatment of morphea.

Abstract

A 5-year-old girl presented with a 2-month history of an indurated hypopigmented, atrophic plaque of biopsy-documented morphea over the right hip area. Previous treatment with 0,1% betamethasone valerate cream twice a day for 3 months failed to improve the lesion. She was treated with calcipotriol ointment twice daily, with nightly occlusion to the plaque for 9 months, and this resulted in resolution. No side effects were noted.

• Authors: Y K Tay
• Journal: The Journal of dermatological treatment (J Dermatolog Treat) Vol. 14 Issue 4 Pg. 219-21 (Dec 2003) ISSN: 0954-6634 [Print] England
• PMID: 14660267 (Publication Type: Case Reports, Journal Article)

Chemical References

• calcipotriene
• Calcitriol

Topics

• Administration, Topical
• Biopsy, Needle
• Calcitriol (analogs & derivatives, therapeutic use)
• Child, Preschool
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Female
• Follow-Up Studies
• Humans
• Immunohistochemistry
• Scleroderma, Localized (drug therapy, pathology)
• Severity of Illness Index
• Treatment Outcome