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Acanthamoeba keratitis as a complication of orthokeratology.

AbstractPURPOSE:
To present four cases of Acanthamoeba keratitis as a complication of orthokeratology.
DESIGN:
Observational case report.
METHODS:
Four patients with Acanthamoeba keratitis had histories of overnight orthokeratology lens wear of 6 months to 2 years.
RESULTS:
Three cases were diagnosed with Acanthamoeba keratitis by corneal scraping and one by confocal microscopy examination. The patients were treated with chlorhexidine, metronidazole, and neomycin sulfate, resulting in a rapid resolution of ocular inflammation.
CONCLUSION:
Overnight wear of orthokeratology lenses may induce Acanthamoeba keratitis.
AuthorsSun Xuguang, Chen Lin, Zhang Yan, Wang Zhiqun, Li Ran, Luo Shiyun, Jin Xiuying
JournalAmerican journal of ophthalmology (Am J Ophthalmol) Vol. 136 Issue 6 Pg. 1159-61 (Dec 2003) ISSN: 0002-9394 [Print] United States
PMID14644232 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Infective Agents
  • Metronidazole
  • Neomycin
  • Chlorhexidine
Topics
  • Acanthamoeba (isolation & purification)
  • Acanthamoeba Keratitis (diagnosis, drug therapy, etiology)
  • Adolescent
  • Adult
  • Animals
  • Anti-Infective Agents (therapeutic use)
  • Chlorhexidine (therapeutic use)
  • Contact Lenses (adverse effects)
  • Cornea (parasitology)
  • Drug Therapy, Combination
  • Female
  • Humans
  • Male
  • Metronidazole (therapeutic use)
  • Myopia (therapy)
  • Neomycin (therapeutic use)

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