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Contact orofacial granulomatosis caused by delayed hypersensitivity to gold and mercury.

Abstract
Orofacial granulomatosis, an entity with characteristic clinicopathologic features, is thought to be a reactive process. The authors describe orofacial granulomatosis associated with contact allergy to gold in dental crowns in one patient and a possible allergic contact reaction to mercury from dental fillings in another one. Thus allergic contact dermatitis to the metals gold and mercury should be considered as a possible etiologic agent of orofacial granulomatosis.
AuthorsAneta Lazarov, Dvora Kidron, Zeev Tulchinsky, Benny Minkow
JournalJournal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 49 Issue 6 Pg. 1117-20 (Dec 2003) ISSN: 0190-9622 [Print] United States
PMID14639396 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Gold Alloys
  • Mercury Compounds
  • Dental Amalgam
Topics
  • Adult
  • Aged
  • Crowns
  • Dental Amalgam (adverse effects)
  • Dermatitis, Allergic Contact (etiology)
  • Dermatitis, Contact (etiology)
  • Facial Dermatoses (etiology)
  • Female
  • Gold Alloys (adverse effects)
  • Granuloma (etiology)
  • Humans
  • Lip Diseases (etiology)
  • Mercury Compounds (adverse effects)
  • Mouth Diseases (etiology)

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