[An open non-comparative study of the efficacy and tolerability of sultamicillin in the therapy of respiratory infections in childhood].

Abstract

Forty-eight children (25 males + 23 females), mean age 3.5 years +/- 2.6 (range 1-11), were treated for the following respiratory infections: pharyngotonsillitis (9), bronchitis (18), bronchopneumonia (14), asthmatic bronchitis (4) and pneumonia (3). The average duration of treatment was 5.3 +/- 2.0 days (range 3-13). Sultamicillin was administered at the dose of 50 mg/kg/day. Patients with fever experienced a defervescence on the second day of therapy. Forty-six children (96%) showed a good clinical response. The tolerability of the drug was excellent or good in 93.8% of the cases.

• Authors: C Cocchi, D Seracini, G Bartolozzi
• Journal: La Clinica terapeutica (Clin Ter) Vol. 141 Issue 9 Pg. 183-6 (Sep 1992) ISSN: 0009-9074 [Print] Italy
• Vernacular Title: Studio aperto non comparativo dell'efficacia e tollerabilità della sultamicillina nella terapia delle infezioni respiratorie in età pediatrica.
• PMID: 1458803 (Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article)

Chemical References

• sultamicillin
• Ampicillin
• Sulbactam

Topics

• Age Factors
• Ampicillin (administration & dosage, therapeutic use)
• Child
• Child, Preschool
• Drug Therapy, Combination (administration & dosage, therapeutic use)
• Drug Tolerance
• Female
• Humans
• Infant
• Male
• Respiratory Tract Infections (drug therapy)
• Sulbactam (administration & dosage, therapeutic use)
• Time Factors