[Two cases of radiation myositis probably induced by recall phenomenon].

Abstract

Two cases of radiation myositis following gemcitabine-based chemotherapy for advanced non-small cell lung cancer are presented. In the two cases, myositis appeared 3 and 5.5 months after the completion of radiation therapy and 2 and 2.5 months after the beginning of chemotherapy, respectively. The affected areas, the upper back and right thigh, appeared as areas of increased signal intensity on T2-weighted MR imaging and were enhanced by the administration of Gd-DTPA in the skeletal muscles. These coincided with the previously irradiated area. Although radiation myositis is a rare complication, it is important to be careful of radiation recall induced by chemotherapeutic agents.

• Authors: Gouji Miura, Tsuneo Matsumoto, Nobuyuki Tanaka, Takuya Emoto, Takeo Kawamura, Naofumi Matsunaga
• Journal: Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica (Nihon Igaku Hoshasen Gakkai Zasshi) Vol. 63 Issue 8 Pg. 420-2 (Sep 2003) ISSN: 0048-0428 [Print] Japan
• PMID: 14587415 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antimetabolites, Antineoplastic
• Radiation-Sensitizing Agents
• Deoxycytidine
• Gemcitabine

Topics

• Aged
• Antimetabolites, Antineoplastic (adverse effects)
• Carcinoma, Non-Small-Cell Lung (drug therapy, radiotherapy)
• Combined Modality Therapy
• Deoxycytidine (adverse effects, analogs & derivatives)
• Humans
• Lung Neoplasms (drug therapy, radiotherapy)
• Male
• Middle Aged
• Myositis (etiology)
• Radiation-Sensitizing Agents (adverse effects)
• Radiotherapy (adverse effects)
• Gemcitabine