[The effect of a different energy supply on the growth intensity and skeletal development of growing Great Danes. 2. Effect on insulin-like growth factor I and on thyroid hormones].

Abstract

In an experiment with 13 growing Great Danes (littermates) fed ad libitum (4 dogs) or restrictively (70% of ad libitum energy intake; 9 dogs), concentrations of insulin-like growth factor I (IGF-I), 3,5,3'-triiodothyronine (T3) and thyroxine (T4) were measured in blood samples until the age of 6 months. In the ad libitum fed group, levels of T3 and T4 were partially and of IGF-I were significantly (p < 0.01) elevated as compared with the control dogs. Postprandial changes of IGF-I were absent in growing Great Danes as well as in a reference group of 3 adult beagles. Increased concentrations of IGF-I, T3 and T4 could be causally related to osteochondrosis, which frequently occurs in intensively fed dogs.

• Authors: J W Blum, J Zentek, H Meyer
• Journal: Zentralblatt fur Veterinarmedizin. Reihe A (Zentralbl Veterinarmed A) Vol. 39 Issue 8 Pg. 568-74 (Oct 1992) ISSN: 0514-7158 [Print] Germany
• Vernacular Title: Untersuchungen zum Einfluss einer unterschiedlichen Energieversorgung auf die Wachstumsintensität und Skelettenwicklung bei wachsenden Doggen. 2. Mitteilung: Einfluss auf den insulinähnlichen Wachstumsfaktor I und auf Schilddrüsenhormone.
• PMID: 1455924 (Publication Type: English Abstract, Journal Article)

Chemical References

• Thyroid Hormones
• Insulin-Like Growth Factor I

Topics

• Animal Feed
• Animals
• Bone Development
• Breeding
• Dogs (growth & development)
• Energy Intake (physiology)
• Insulin-Like Growth Factor I (analysis)
• Thyroid Hormones (blood)