[Effect of colloid bismuth treatment on Campylobacter pylori infection of the gastric mucosa and the clinical course of non-ulcer dyspepsia].

Abstract

There are suggestions, that the idiopathic non-ulcer dyspepsia is related to the chronic gastritis type B coexisting with C. pylori infection. Presented studies were aimed at the assessing of an effect of the treatment with De-Nol on the course of the idiopathic non-ulcer dyspepsia of C. pylori infection. Gastroscopic examination was performed in 52 patients with non-ulcer dyspepsia before and after the treatment with De-Nol administered for 4-8 weeks. Campylobacter pylori was isolated from 71% of patients with idiopathic non-ulcer dyspepsia. An infection was eradicated in 97.4% of patients treated with De-Nol. The number of dyspeptic episodes decreased in by 96% of patients, including 33% of patients in whom total recovery was noted. De-Nol was well tolerated. De-Nol is highly effective in the eradication of C. pylori and produces clinical improvement in the majority of patients with non-ulcer dyspepsia.

• Authors: J Muszyński, D Biernacka, E Bogacka-Zatorska, M Stepka, A Galczak, L Zalewski, K Lissowska, A Ehrmann
• Journal: Polski tygodnik lekarski (Warsaw, Poland : 1960) (Pol Tyg Lek) 1992 Jan 20-27 Vol. 47 Issue 3-4 Pg. 75-8 ISSN: 0032-3756 [Print] Poland
• Vernacular Title: Wpływ leczenia bizmutem koloidalnym na zakaåenie błony śluzowej zoładka przez Campylobacter pylori i przebieg kliniczny idiopatycznej dyspepsji niewrzodowej.
• PMID: 1437790 (Publication Type: Clinical Trial, English Abstract, Journal Article)

Chemical References

• Antacids
• Organometallic Compounds
• bismuth tripotassium dicitrate

Topics

• Adolescent
• Adult
• Aged
• Antacids (therapeutic use)
• Chronic Disease
• Dyspepsia (drug therapy, etiology)
• Female
• Gastric Mucosa (drug effects)
• Gastritis (complications, drug therapy)
• Helicobacter Infections (complications, drug therapy)
• Humans
• Male
• Middle Aged
• Organometallic Compounds (therapeutic use)