Improvement of the exercise test after therapy in thyrotoxic periodic paralysis.

Abstract

The diagnosis of periodic paralysis (PP) can be aided by demonstrating a decrease in compound motor action potential (CMAP) amplitude after several minutes of exercise. We report a case of secondary hypokalemic PP due to thyrotoxicosis in which the decrease in the CMAP amplitude after exercise dramatically improved after treatment, when a euthyroid state was achieved. The exercise test is a useful electrophysiologic means of monitoring the neuromuscular status of patients with thyrotoxic periodic paralysis prior to, and after treatment of the thyrotoxicosis.

• Authors: C E Jackson, R J Barohn
• Journal: Muscle & nerve (Muscle Nerve) Vol. 15 Issue 10 Pg. 1069-71 (Oct 1992) ISSN: 0148-639X [Print] United States
• PMID: 1406763 (Publication Type: Case Reports, Journal Article)

Chemical References

• Iodine Radioisotopes

Topics

• Action Potentials
• Adult
• Electromyography
• Exercise Test
• Humans
• Hypokalemia (etiology)
• Iodine Radioisotopes (therapeutic use)
• Male
• Muscles (physiopathology)
• Paralysis (diagnosis, etiology)
• Thyrotoxicosis (complications, diagnosis, radiotherapy)