Dowling-Degos' disease mimicking chloracne.

Abstract

We describe a patient with clinical features that resembled severe chloracne; however, histopathologic findings revealed a reticulated pigmented anomaly. Innumerable comedones, many cysts, acneiform scarring, and flexural and facial pigmentation were noted in this patient, who is a machinist. A serum test for polychlorinated biphenyl was negative, which eliminated a diagnosis of chloracne. The spectrum of clinical features of the histologically well-defined Dowling-Degos' disease is discussed; in this disease lesions can be flexural or acral and can appear as macules, comedones, or cysts.

• Authors: J Kershenovich, A Langenberg, R B Odom, P E LeBoit
• Journal: Journal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 27 Issue 2 Pt 2 Pg. 345-8 (Aug 1992) ISSN: 0190-9622 [Print] United States
• PMID: 1387658 (Publication Type: Case Reports, Journal Article)

Chemical References

• Polychlorinated Biphenyls

Topics

• Acne Vulgaris (chemically induced, pathology)
• Diagnosis, Differential
• Humans
• Male
• Middle Aged
• Pigmentation Disorders (pathology)
• Polychlorinated Biphenyls (adverse effects)