Immunohistochemical evaluation of oral myxoid lesions.

Abstract

Oral examples of neurothekeomas (nerve sheath myxomas), soft tissue myxomas, and focal mucinous and odontogenic myxomas were examined for selected markers. With the use of avidin-biotin complex staining procedures, these specimens of lesions were stained with antibodies to S-100 protein, neurospecific enolase, neurofilaments, desmin, and vimentin. Our results show that the use of immunohistochemical markers for these neural antigens can aid in distinguishing nerve sheath myxomas from other oral myxoid lesions.

• Authors: T L Green, S M Leighty, R Walters
• Journal: Oral surgery, oral medicine, and oral pathology (Oral Surg Oral Med Oral Pathol) Vol. 73 Issue 4 Pg. 469-71 (Apr 1992) ISSN: 0030-4220 [Print] United States
• PMID: 1374171 (Publication Type: Journal Article)

Chemical References

• Biomarkers, Tumor
• Desmin
• Mucins
• S100 Proteins
• Vimentin
• Phosphopyruvate Hydratase

Topics

• Biomarkers, Tumor (analysis)
• Desmin (chemistry)
• Humans
• Immunohistochemistry
• Intermediate Filaments (chemistry)
• Mouth Diseases (metabolism)
• Mouth Neoplasms (chemistry)
• Mucins (analysis)
• Myxoma (chemistry)
• Neurilemmoma (chemistry)
• Odontogenic Tumors (chemistry)
• Phosphopyruvate Hydratase (analysis)
• S100 Proteins (analysis)
• Soft Tissue Neoplasms (chemistry)
• Staining and Labeling
• Vimentin (chemistry)