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Induction of remission in a patient with Takayasu's arteritis by low dose pulses of methotrexate.

Abstract
A 42 year old woman with Takayasu's arteritis responded to treatment with prednisone (60 mg daily) but developed severe side effects. Cyclophosphamide treatment did not produce a clinical improvement or steroid sparing effect. A treatment trial with a weekly pulse of low dose methotrexate improved her symptoms and the patency of her occluded left subclavian artery.
AuthorsD Mevorach, G Leibowitz, M Brezis, E Raz
JournalAnnals of the rheumatic diseases (Ann Rheum Dis) Vol. 51 Issue 7 Pg. 904-5 (Jul 1992) ISSN: 0003-4967 [Print] England
PMID1352962 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Prednisolone
  • Methotrexate
Topics
  • Administration, Oral
  • Adult
  • Drug Administration Schedule
  • Female
  • Humans
  • Methotrexate (administration & dosage)
  • Prednisolone (therapeutic use)
  • Remission Induction (methods)
  • Takayasu Arteritis (drug therapy)

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