Abstract |
The conventional diagnosis of cholera depends on complex bacteriological procedures. Coagglutination is a simple, rapid, inexpensive and efficient technique for the presumptive diagnosis of cholera. Of 840 fecal samples from suspected cases of cholera examined at Tabatinga (State of Amazonas, Brazil) 31 (3.6%) were confirmed by culture and 29 of them were also positive by the coagglutination test performed directly on the fecal enrichment broth (alkaline peptone water). About 90% of the positive coagglutination results were obtained after 5-h incubation at 37 degrees C and the sensitivity, specificity and accuracy of the method were 93.5%, 99% and 98.8%, respectively. Relative to the culture results, coagglutination yielded two false-negative and eight false-positive results. The coagglutination test for cholera can provide a rapid and reliable tool for epidemiological studies and for the planning of more effective measures against cholera.
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Authors | J R Andrade, J L da-Silva, M F Barbosa, C A Caldas |
Journal | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas
(Braz J Med Biol Res)
Vol. 25
Issue 4
Pg. 375-8
( 1992)
ISSN: 0100-879X [Print] Brazil |
PMID | 1342214
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Topics |
- Agglutination Tests
- Brazil
- Cholera
(diagnosis)
- False Negative Reactions
- False Positive Reactions
- Humans
- Sensitivity and Specificity
- Time Factors
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