Use of MAC-ELISA for evaluation of yellow fever vaccination.

Abstract

An evaluation of the IgM antibody immune response against yellow fever using strain 17D was carried out by MAC-ELISA and PRNT. The results showed an agreement of 97% between both tests and the authors conclude that MAC-ELISA can be used as a specific and sensitive assay to replace the PRNT for detecting yellow fever antibodies in human sera, after vaccination programs.

• Authors: R M Nogueira, H G Schatzmayr, M P Miagostovich, S M Cavalcanti, R de Carvalho
• Journal: Revista do Instituto de Medicina Tropical de Sao Paulo (Rev Inst Med Trop Sao Paulo) 1992 Sep-Oct Vol. 34 Issue 5 Pg. 447-50 ISSN: 0036-4665 [Print] Brazil
• PMID: 1342109 (Publication Type: Comparative Study, Journal Article)

Chemical References

• Antibodies, Viral
• Viral Vaccines

Topics

• Antibodies, Viral (blood)
• Dengue (immunology)
• Enzyme-Linked Immunosorbent Assay
• Evaluation Studies as Topic
• Hemolytic Plaque Technique
• Humans
• Neutralization Tests
• Viral Vaccines (immunology)
• Yellow Fever (immunology)
• Yellow fever virus (immunology)