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In situ hybridization with digoxigenin-labelled DNA probes for the detection of human papillomavirus-induced focal epithelial hyperplasia among Venezuelans.

Abstract
An in situ hybridization assay with digoxigenin-labelled probes was used to detect the presence of human papillomavirus (HPV) sequences in ten related Venezuelan patients with the diagnosis of focal epithelial hyperplasia. The samples displayed HPV sequences in all cases. Further restriction analysis in four of the patients suggested the presence of HPV-13 in oral lesions.
AuthorsG Premoli-de-Percoco, I Galindo, J L Ramirez
JournalVirchows Archiv. A, Pathological anatomy and histopathology (Virchows Arch A Pathol Anat Histopathol) Vol. 420 Issue 4 Pg. 295-300 ( 1992) ISSN: 0174-7398 [Print] Germany
PMID1314447 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • DNA Probes
  • Digoxigenin
Topics
  • Adolescent
  • Adult
  • Child
  • DNA Probes (genetics)
  • Digoxigenin
  • Female
  • Humans
  • Hyperplasia (diagnosis)
  • Male
  • Mouth Mucosa (microbiology, pathology)
  • Nucleic Acid Hybridization
  • Papillomaviridae (genetics, isolation & purification)
  • Retrospective Studies
  • Tumor Virus Infections (diagnosis, microbiology, pathology)
  • Venezuela

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