Hepaticopancreaticogastroduodenectomy with transplantation for metastatic islet cell carcinoma in childhood.

Abstract

Symptomatic islet cell carcinoma of the pancreas with liver metastasis, a rare tumor cured only by complete resection, was unresponsive to chemotherapy and was treated with hepaticopancreaticogastroduodenectomy en bloc resection with transplantation in an 11-year-old girl. This radical surgery in conjunction with adjuvant chemotherapy and interstitial and external beam irradiation has resulted in symptomatic relief and no evidence of disease at 15 months posttransplant.

• Authors: T E Lobe, S R Vera, L C Bowman, J Fontanesi, L G Britt, A O Gaber
• Journal: Journal of pediatric surgery (J Pediatr Surg) Vol. 27 Issue 2 Pg. 227-9 (Feb 1992) ISSN: 0022-3468 [Print] United States
• PMID: 1314308 (Publication Type: Case Reports, Journal Article)

Topics

• Adenoma, Islet Cell (secondary, surgery)
• Anastomosis, Surgical
• Child
• Combined Modality Therapy
• Duodenum (transplantation)
• Female
• Humans
• Jejunum (surgery)
• Liver Neoplasms (secondary, surgery)
• Liver Transplantation (methods)
• Pancreas Transplantation (methods)
• Pancreatic Neoplasms (surgery)
• Spleen (transplantation)
• Stomach (transplantation)