[Gingival hyperplasia induced by cyclosporin A].

Abstract

Cyclosporine-A (Cy-A) selectively inhibits T cell function with minimal effect on humoral immunity. It is used specially in transplantation patients and in some cases, like other drugs, it causes gingival hyperplasia. In this article, after a review of the most recent pathogenetic hypothesis, the authors present their experience based on 10 cases of gingival hyperplasia in kidney transplantation patients in treatment with Cy-A.

• Authors: V Cervelli, F Guidiceandrea, G M Pigliucci, D Venditti, B Iorio, M Grimaldi, C U Casciani
• Journal: Rivista europea per le scienze mediche e farmacologiche = European review for medical and pharmacological sciences = Revue europeenne pour les sciences medicales et pharmacologiques (Riv Eur Sci Med Farmacol) 1992 Jul-Aug Vol. 14 Issue 4 Pg. 257-9 ISSN: 0392-291X [Print] Italy
• Vernacular Title: Iperplasia gengivale indotta da ciclosporina-A.
• PMID: 1306002 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cyclosporine

Topics

• Adolescent
• Adult
• Child
• Cyclosporine (adverse effects)
• Female
• Gingival Hyperplasia (chemically induced, pathology)
• Humans
• Male