Fatty liver with elevated transaminase levels due to heterozygous apolipoprotein B deficiency.

Elevation of transaminase levels in asymptomatic subjects could be due to a common benign condition such as fatty liver or a more serious disease such as chronic hepatitis due to various causes; in some subjects a liver biopsy is indicated. Heterozygous apolipoprotein B deficiency is an uncommon cause of transaminase elevation, as indicated by low levels of cholesterol and low density lipoprotein-cholesterol. This should be noted to avoid unnecessary investigations (including liver biopsy) in asymptomatic subjects with persistent elevation of transminase levels in the serum.
AuthorsT M Artekar, H G Desai
JournalTropical gastroenterology : official journal of the Digestive Diseases Foundation (Trop Gastroenterol) 2003 Jan-Mar Vol. 24 Issue 1 Pg. 35-6 ISSN: 0250-636X [Print] India
PMID12974215 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Apolipoproteins B
  • Transaminases
  • Adult
  • Apolipoproteins B (deficiency)
  • Fatty Liver (blood, diagnosis, etiology)
  • Humans
  • Liver (pathology)
  • Male
  • Transaminases (blood)

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