[The function of 2 detoxifying body systems in workers of the petrochemical industry].

Abstract

Studies of the immune status and antipyrine test helped to analyse the status of the two body detoxicants--the immune system and the system of microsomal hepatic oxygenases in petrochemical production workers suffering from the chronic bronchitis and bronchial asthma. Immune deficiency of T and B cells, decreased function of cytochrome P-450 containing monooxygenase system were revealed, which indicates complicated relations between the two body detoxicant systems.

• Authors: A L Mazurov, G V Potapova, E V Saprykina, A F Ershov
• Journal: Gigiena truda i professional'nye zabolevaniia (Gig Tr Prof Zabol) Issue 8 Pg. 16-8 ( 1992) ISSN: 0016-9919 [Print] Russia (Federation)
• Vernacular Title: Sostoianie dvukh detoksitsiruiushchikh sistem organizma u rabotnikov neftekhimicheskogo proizvodstva.
• PMID: 1295791 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Petroleum
• Cytochrome P-450 Enzyme System
• Antipyrine

Topics

• Adult
• Antipyrine (pharmacokinetics)
• Asthma (physiopathology)
• Bronchitis (physiopathology)
• Chemical Industry
• Chronic Disease
• Cytochrome P-450 Enzyme System (metabolism)
• Female
• Humans
• Immune System (physiopathology)
• Inactivation, Metabolic
• Male
• Microsomes, Liver (enzymology)
• Middle Aged
• Occupational Diseases (physiopathology)
• Occupational Exposure (adverse effects)
• Petroleum