Magnetoencephalographic studies of two cases of diffuse subcortical laminar heterotopia or so-called double cortex.

Abstract

Two cases (a young male and a girl, suffering intractable epilepsy) of diffuse subcortical laminar heterotopia, or so-called double cortex (DC) have been investigated using magnetoencephalography (MEG). MEG confirmed involvement of both cortices (hetero- and normocortex) in the genesis of interictal spikes, and, according to the heterogeneity of DC syndrome, some differences were observed: spike initiation in the normocortex and latter involvement of the heterotopic cortex in the man, and rather a cancellation in both cortices in the girl. In addition, participation of heterotopic cortex in physiological activities could be demonstrated in the man.

• Authors: Pierre Toulouse, Cyril Agulhon, Delphine Taussig, Sylvia Napuri, Arnaud Biraben, Pierre Jannin, Michel Carsin, Jean-Marie Scarabin
• Journal: NeuroImage (Neuroimage) Vol. 19 Issue 4 Pg. 1251-9 (Aug 2003) ISSN: 1053-8119 [Print] United States
• PMID: 12948686 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Brain Mapping
• Cerebral Cortex (physiopathology)
• Child
• Choristoma
• Epilepsies, Partial (congenital, physiopathology)
• Epilepsy, Generalized (congenital, physiopathology)
• Evoked Potentials, Auditory (physiology)
• Evoked Potentials, Somatosensory (physiology)
• Female
• Humans
• Image Processing, Computer-Assisted
• Imaging, Three-Dimensional
• Infant
• Magnetic Resonance Imaging
• Male
• Spasms, Infantile (congenital, physiopathology)