Abstract |
This investigation reports the long-term use of the antiandrogen cyproterone acetate (CPA) in a pedophile, who was studied continuously over 38 months. Measures of sexual arousal, serum testosterone, and gonadotropin levels were significantly reduced by the drug as compared with placebo and no treatment; prolactin levels were significantly elevated. Some workers have observed that long-term administration of CPA (more than one year, which was then discontinued) produced enduring (in some cases apparently permanent) anti-libidinal effects; however, in the case described, within three weeks of stopping the drug, all measures had returned to pretrial levels. The importance of continuous long-term monitoring in sex offenders receiving an antiandrogen is discussed.
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Authors | A J Cooper, Z Cernovsky, R V Magnus |
Journal | Journal of sex & marital therapy
(J Sex Marital Ther)
Vol. 18
Issue 4
Pg. 292-302
( 1992)
ISSN: 0092-623X [Print] England |
PMID | 1291700
(Publication Type: Case Reports, Clinical Trial, Controlled Clinical Trial, Journal Article)
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Chemical References |
- Gonadotropins, Pituitary
- Testosterone
- Cyproterone Acetate
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Topics |
- Adult
- Cyproterone Acetate
(administration & dosage, pharmacology, therapeutic use)
- Gonadotropins, Pituitary
(blood)
- Humans
- Libido
(drug effects)
- Male
- Pedophilia
(blood, drug therapy)
- Penile Erection
(drug effects)
- Testosterone
(blood)
- Time Factors
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